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Titlebook: Reproductive Immunology; Lars B. Olding Book 1997 The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Ver

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发表于 2025-3-21 16:53:07 | 显示全部楼层 |阅读模式
书目名称Reproductive Immunology
编辑Lars B. Olding
视频video
丛书名称Current Topics in Microbiology and Immunology
图书封面Titlebook: Reproductive Immunology;  Lars B. Olding Book 1997 The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Ver
描述Discrimination of self from nonself is the major function of the immune system and understanding the mechanism(s) involved a main employer of immunologists. Hence, the age-old puzzle of why a fetus that contains a panel of major histocompatibility (MHC) antigens derived from its mother and its father is not rejected (spontaneously aborted) by lymphocytes from its mother who should theoretically recognize foreign MHC molecules from the father has remained of great interest. This dilemma has enticed immunologists and developmental biologists for many years. This volume was created to present the information currently on hand in this subject to the scientific public. The guest editor, Professor Lars Olding, has a long and distinguished history of contributions in this field, having been one of the main propo­ nents of the argument that lymphocytes from the fetus play an active role in this process by suppressing lymphocytes from the mother from proliferating and thereby acting as killer cells. His work has defined the phenomenon and identified suppressor molecules (factors) involved in the process. In a different but related chapter, Margareta Unander extends such observations to the
出版日期Book 1997
关键词Antigen; Fortpflanzung; Immunität; fetus; genetics; immunity; lymphocytes; placenta; plazenta; pregnancy; repr
版次1
doihttps://doi.org/10.1007/978-3-642-60614-4
isbn_softcover978-3-642-64475-7
isbn_ebook978-3-642-60614-4Series ISSN 0070-217X Series E-ISSN 2196-9965
issn_series 0070-217X
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE
The information of publication is updating

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发表于 2025-3-21 21:47:35 | 显示全部楼层
Immunogenetics of Reproduction:An Overview,LA genes is associated with rapid rejection of foreign tissues(. R. and C. 1990; R. et al. 1991). A notable exception is pregnancy, during which allogeneic(fetal) tissues escape rejection. The immunologically privileged nature of the fetal allograft was first noted by M. in 1953, and maternal tolera
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Immunobiology of the Decidua,t to develop to maturity, at which point it is born alive(B. 1983). In different species the details of the embryo-uterine lining interactions differ. In primates and rodents trophoblast cells which form the outer layer of the preimplanting blastocyst attach to the uterine epithelium, invade or dest
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Maternal T Cell Reactivity in Pregnancy?,riefly) only on data in such situations when they cast light on maternal T cell status in normal human pregnancy. It is necessary, however, to deal with abortion models in mice since these are models for study of T cell reactivity during gestation.
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Suppressive Cellular and Molecular Activities in Maternofetal Immune Interactions; Suppressor Cell ally accepted by her as a “semi-allograft”. Several models have been proposed to explain this apparent paradox. B. (1964) concept of the fetoplacental unit as a semi-allograft is still valid form a purely genetic point of view, but otherwise has some shortcomings. First, in contrast to a grafted org
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