书目名称 | Rejuvenation and Longevity | 副标题 | Introduction to Reju | 编辑 | Khachik K. Muradian,Vadim E. Fraifeld | 视频video | http://file.papertrans.cn/827/826042/826042.mp4 | 概述 | Presents a balanced and scientific approach to the mirage of immortality and ever-lasting youth.Analyzes the current knowledge base of biological processes related to rejuvenation.Discusses in a syste | 丛书名称 | Healthy Ageing and Longevity | 图书封面 |  | 描述 | .This book is a systematic collection and critical analysis of current information on rejuvenation, starting from the evolutionary aspects of the origin of life, immortality, and aging. Models, mechanisms, and types of rejuvenation are the key subjects of the book. Processes like cellular reprogramming, resetting of the aging clock, immortal unicellulars and cell cultures are explored through the lens of rejuvenation. Recent discoveries in this field offer a nuanced view of rejuvenation that has fascinated mankind since early history...There is evidence, though still controversial, indicating that biological time could be reversible. Indeed, under specific experimental conditions, cells can be moved back and forth along the age axis. Differentiation status and replicative age of cells can be modified not only by defined transcription factors, but also by ‘cocktails’ of small molecules originating from natural substances or well-known longevity-promoting drugs. Still in its infancy, such findings open up the perspective of .in vivo. rejuvenation trials. Special attention is given to the quasi-immortal and extremely long-lived multicellular animal species as well as to the role of re | 出版日期 | Book 2024 | 关键词 | Immortality; Experimental models; Rejuvenation; Reprogramming; Aging; Longevity | 版次 | 1 | doi | https://doi.org/10.1007/978-3-031-64995-0 | isbn_softcover | 978-3-031-64997-4 | isbn_ebook | 978-3-031-64995-0Series ISSN 2199-9007 Series E-ISSN 2199-9015 | issn_series | 2199-9007 | copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl |
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