书目名称 | Regulatory RNAs | 副标题 | Basics, Methods and | 编辑 | Bibekanand Mallick,Zhumur Ghosh | 视频video | | 概述 | Complete overview on regulatory RNAs.Includes the basics, methods and applicative areas involving these regulatory RNAs.Written by international experts.Includes supplementary material: | 图书封面 |  | 描述 | .Recent progress in high-throughput technologies and genome wide transcriptome studies have lead to a significant scientific milestone of discovering non-coding RNAs (ncRNAs) which spans through a major portion of the genome. These RNAs most often act as riboregulators, and actively participate in the regulation of important cellular functions at the transcriptional and/or post-transcriptional levels rather than simply being an intermediated messenger between DNA and proteins. As the appreciation for the importance of ncRNAs continues to emerge, it is also increasingly clear that these play critical roles in gene regulatory processes during development and differentiation. Further, regulatory RNAs are useful biomarkers for diagnosis of diseases. Hence these RNA regulators are essential to the development of therapeutics. This book on “Regulatory RNAs” offers a comprehensive view on our current understanding of these regulatory RNAs viz. siRNA, miRNA, piRNA, snoRNA, long non-coding RNA, small RNA etc. It addresses both the biogenesis and mechanism of action of regulatory RNAs with a primary focus on their annotation, experimental methodologies (microarray, next-gen sequencing etc.) | 出版日期 | Book 2012 | 关键词 | non-coding RNAs; regulatory RNAs; small RNAs; gene expression | 版次 | 1 | doi | https://doi.org/10.1007/978-3-642-22517-8 | isbn_softcover | 978-3-642-44284-1 | isbn_ebook | 978-3-642-22517-8 | copyright | Springer-Verlag Berlin Heidelberg 2012 |
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