书目名称 | Regulation of Inflammatory Signaling in Health and Disease | 编辑 | Dakang Xu | 视频video | | 概述 | Covers cutting-edge research in innate immunity.Reviews novel mechanisms in regulation of inflammation, such as microRNA and epigenetics.Discussing newly emerged innate lymphoid cells, which bridges i | 丛书名称 | Advances in Experimental Medicine and Biology | 图书封面 |  | 描述 | .This book discusses recent research in innate immunity, which has revealed a large number of receptors that sense the presence of microorganisms or cellular damage in tissues. In complex tissues, many of these sensing events occur simultaneously. Thus, the downstream signaling pathways need to be integrated so that an appropriate cellular inflammatory response can be initiated. In addition, the inflammasome defines the molecular and cellular processes of inflammation in response to microbial infection. Previous data suggested that regulation of inflammasomes is mediated by microbes, but inflammasomes also have antimicrobial functions. Increasing evidence in mouse models, together with human data, strongly implicates an involvement of the inflammasome and uncontrolled inflammation in the initiation and progression of diseases with a high impact on public health. . .The book reviews novel aspects of functional genomics, epigenomics, transcriptomics, post-translat.ional modifications, microbiome and immunometabolism in order to understand inflammatory signaling and responses, covering recent findings on the mechanisms underlying the regulation of inflammatory responses to pathogens, | 出版日期 | Book 2017 | 关键词 | Inflammatory signaling and disease; Epigenetics regulation; Inflammasomes; Post-translational Modificat | 版次 | 1 | doi | https://doi.org/10.1007/978-981-10-5987-2 | isbn_softcover | 978-981-13-5543-1 | isbn_ebook | 978-981-10-5987-2Series ISSN 0065-2598 Series E-ISSN 2214-8019 | issn_series | 0065-2598 | copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Singapor |
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