Titlebook: Regulation of Hepatic Metabolism; Intra- and Intercell Ronald G. Thurman,Frederick C. Kauffman,Kurt Junge Book 1986 Plenum Press, New York

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Histology and Histochemistryl and histochemical techniques that in the past have been the subject of almost encyclopedic volumes.. The methods selected for description herein include the most frequently used techniques of tissue pretreatment, histological staining, quantitative histology, and qualitative and quantitative histo

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Separation of Functionally Different Liver Cell Types types identified, the hepatocytes (parenchymal cells) contribute more than 90% to the total volume occupied by liver cells.. The nonhepatocytes or non-parenchymal cells are much smaller than the hepatocytes and constitute about 40% of the cells by number. They consist of sinusoidal cells, i.e., Kup

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Metabolism of Carbohydratesch meal, via glycogen synthesis and glycolysis plus liponeogenesis, and it liberates glucose if needed, as between meals, via glycogen degradation and gluconeo-genesis. It alone produces ketone bodies and has a major role in lipoprotein metabolism (see Chapter 10). The liver detoxifies ammonia and a

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Lobular Oxygen Gradients: Possible Role in Alcohol-Induced Hepatotoxicityge. The purpose of this chapter is to evaluate the evidence for and against the hypothesis that hypoxia is involved in this disease. We shall review hepatic oxygen uptake, ethanol metabolism and adaptations, and hypoxic tissue damage in general briefly.

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Biotransformation and Zonal Toxicityure (for a comprehensive review, see Zimmerman1). Products of plant, fungal, and bacterial metabolism, minerals,. chemicals and pharmaceuticals, industrial byproducts, and waste materials can damage the liver.. The types of hepatic injury that result from exposure to hepatotoxins are quite diverse.

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