| 书目名称 | Regulation of Gene Expression in the Tumor Environment |
| 副标题 | Regulation of melano |
| 编辑 | Menashe Bar-Eli (Dr) |
| 视频video | |
| 概述 | Describes the contribution of the tumor microenvironment to tumor growth and metastasis.Gives a unique opportunity to understand the cross talk between tumor cells (the seed) and the organ microenviro |
| 丛书名称 | The Tumor Microenvironment |
| 图书封面 |  |
| 描述 | .It is now becoming very clear that the development and progression of tumor towards the malignant (metastatic) phenotype depends tightly on the interaction between the tumor cells and the tumor microenvironment. Tumor cells respond to stimuli generated within the tumor microenvironment for their growth advantage while the tumor cell themselves reshape and remodel the architecture and function of their extracellular matrices. The term tumor microenvironment is a wide umbrella consisting of stromal cells such as fibroblasts and endothelial cells and infiltration immune cells including T and B cells, macrophages, and other inflammatory cells (PMNs). These different components of the tumor microenvironment could have stimulatory and inhibitory effects on tumor progression by regulating the gene expression repertoire within the tumor cells on one hand and the stroma cells on the other. In this volume we have seven contributors who will discuss several different aspects on the cross talk within the tumor microenvironment components leading to the acquisition of the metastatic phenotype. It is our hope that these state-of-the-art studies will shed further light on our understanding of th |
| 出版日期 | Book 2008 |
| 关键词 | Angiogenesis; Invasion; Macrophages; Metastasis; Tumor Growth; Tumor Microenvironment; regulation |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-1-4020-8341-9 |
| isbn_softcover | 978-90-481-7849-0 |
| isbn_ebook | 978-1-4020-8341-9 |
| copyright | Springer Science+Business Media B.V. 2008 |
发表于 2025-3-21 18:48:46
