Titlebook: Regulation of Carcinogenesis, Angiogenesis and Metastasis by the Proprotein Convertases (PC‘s); A New Potential Stra A-Majid Khatib Book 20

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d and updated information on the role of these molecules in .Convertases are widely expressed activating enzymes involved in various physiological and pathological processes. The purpose of this book is to provide detailed and updated information on the role of these molecules in cancer. This book i

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Signalling Pathways Leading to Furin Expression in Cancer,ignalling pathways involved in the growth and progression of neoplasms. In addition, several factors that modulate the furin-transcriptional unit are being elucidated at the level of cis-acting sequences. Strategies that take advantage of the signalling pathways that regulate furin expression for the treatment of cancer will be discussed

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PACE4 Gene Expression in Human Ovarian Cancer,ry evidence from PACE4 mutant mice strongly suggest that loss of PACE4 production results in ovarian abnormalities, including reduced fertility, premature loss of follicle structures, and abnormal cell morphology with features reminiscent of ovarian tumors

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