| 书目名称 | Regulation of Ca2+-ATPases,V-ATPases and F-ATPases | | 编辑 | Sajal Chakraborti,Naranjan S Dhalla | | 视频video | | | 概述 | A comprehensive investigation into the regulation of Ca2+-ATPases, F-type ATPases, and V-type ATPases.Explores the specific inhibitors and molecular probes for membrane ATPases to improve the therapy | | 丛书名称 | Advances in Biochemistry in Health and Disease | | 图书封面 |  | | 描述 | .The biological membranes of cellular organization enfold an important group of membrane proteins called the ATPases, which are not only versatile in maintaining chemical gradient and electrical potential across the membrane but also bring metabolites necessary for cell metabolism and drive out toxins, waste products and solutes that otherwise can curb cell functions. ATPases are distributed virtually in all live forms starting from unicellular to multicellular and also in viruses. There are different types of ATPases, which differ in function and structure and in the type of ions they transport. The three main types of the ion pump ATPase family are: (i) P-type ATPases that transport different ions across membranes and Ca.2+.ATPases belongs to this catagory (ii) F-type ATPase in mitochondria, chloroplasts and bacterial plasma membranes produce ATP using the proton gradient; and (iii) V-type ATPase catalyzes ATP hydrolysis to transport solutes and maintains acidic pH in organelles like lysosomes. Genetic defects in either of the ATPases cause several diseases and a number of researches have demonstrated the involvement of the members of ATPases in the cell pathology and diseases, t | | 出版日期 | Book 2016 | | 关键词 | Ca2+-ATPases; F-ATPases; V-ATPases; (P)RR/ATP6ap2; Acid-base; Protein Structure | | 版次 | 1 | | doi | https://doi.org/10.1007/978-3-319-24780-9 | | isbn_softcover | 978-3-319-79677-2 | | isbn_ebook | 978-3-319-24780-9Series ISSN 2512-2142 Series E-ISSN 2512-2150 | | issn_series | 2512-2142 | | copyright | Springer International Publishing Switzerland 2016 |
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发表于 2025-3-21 16:34:38
