Titlebook: Regenerative Medicine and Plastic Surgery; Skin and Soft Tissue Dominik Duscher,Melvin A. Shiffman Book 2019 Springer Nature Switzerland AG

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Induction of the Fetal Scarless Phenotype in Adult Wounds: Impossible?rring in the healing of adult cutaneous wounds. This chapter outlines the molecular and cellular processes involved in scarless fetal wound healing and the progress that has been made in recapitulating this process in adult wounds.

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Challenges and Opportunities in Drug Delivery and Wound Healingg localized and sustained drug delivery to the target tissue. In this chapter, we summarize the most promising recent advances in wound healing therapeutics with the corresponding delivery challenges and shed light on possible solutions for effective application.

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Mesenchymal Cells that Support Human Skin Regenerationn instrumental in beginning to understand the complex microenvironment or niche of epidermal stem and progenitors and how it can be manipulated to design more optimal clinical approaches for the treatment of skin deficits.

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Wnt Signaling During Cutaneous Wound Healingrom the control of inflammation and programmed cell death to the mobilization of stem cell reservoirs within the wound site. The influence of secreted Wnt signaling proteins in tissue homeostasis and repair has galvanized efforts to identify small molecules that target Wnt-mediated cellular responses.

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Preparation, Characterization, and Clinical Implications of Human Decellularized Adipose Tissue Extrl to promote the attachment and proliferation of progenitor cells. Creating the optimal microenvironment for tissue regeneration may prove to be tissue specific, and recent research on hDAM manipulation and supplementation with synthetic scaffolds is paving the way for novel therapies in the field of regenerative medicine.