Titlebook: Regenerative Biology of the Eye; Alice Pébay Book 2014 Springer Science+Business Media New York 2014 bionic eye.optic nerve.stem cell ther

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Stem Cells and Regeneration in the , Retina,rces contributing to retinal replacement, the involvement of tissue interactions and the importance of the injury paradigm. We also describe recent progress and promises in the field brought by the development of 3D tissue culture methods and transgenic . models.

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Understanding Retinal Development Can Inform Future Regenerative Therapies, Optic vesicles invaginate to form the two-layered optic cup from which the retinal pigment epithelium (RPE) and neural retina are patterned by a host of extrinsic factors secreted by neighboring cells. Dynamic alterations to the environment of retinal precursor cells direct them to finally form a s

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Stem Cells and Regeneration in the , Retina,tages. Regarding vertebrates, only the newt was thought to exhibit full regenerative capacity upon retinectomy in the adulthood. The recent discovery that the anuran amphibian . can regenerate its retina after metamorphosis opened new avenues to investigate the cellular and molecular mechanisms invo