书目名称 | Recombinant Proteins From Plants | 副标题 | Methods and Protocol | 编辑 | Loïc Faye,Véronique Gomord | 视频video | | 概述 | Fully up-to-date edition offering cutting edge methods for production of recombinant proteins in plants.Provides readily reproducible protocols for researchers in the field of molecular pharming.Inclu | 丛书名称 | Methods in Molecular Biology | 图书封面 |  | 描述 | Altogether, the biochemical, technical and economic limitations on existing proka- otic and eukaryotic expression systems and the growing clinical demand for complex therapeutic proteins have created substantial interest in developing new expression systems for the production of therapeutic proteins. To that end, plants have emerged in the past decade as a suitable alternative to the current production systems, and today their potential for production of high quality, much safer and biologically active complex recombinant pharmaceutical proteins is largely documented. The chapters in this volume, contributed by leaders in the field, sum up the state-- the-art methods for using a variety of different plants as expression hosts for phar- ceutical proteins. Several production platforms are presented, ranging from seed- and leaf-based production in stable transgenic plant lines, to plant cell bioreactors, to viral or Agrobacterium-mediated transient expr ession systems. Currently, antibodies and their derived fragments represent the largest and most important group of biote- nological products in clinical trials. This explains why the potential of most prod- tion platforms is illustrat | 出版日期 | Book 2009 | 关键词 | Chloroplast; Expression; Molecular pharming; Pharming; Plant expression systems; Plant pharming; transgen; | 版次 | 1 | doi | https://doi.org/10.1007/978-1-59745-407-0 | isbn_softcover | 978-1-61737-864-5 | isbn_ebook | 978-1-59745-407-0Series ISSN 1064-3745 Series E-ISSN 1940-6029 | issn_series | 1064-3745 | copyright | Humana Press 2009 |
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