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Titlebook: Recombinant Protein Production with Prokaryotic and Eukaryotic Cells. A Comparative View on Host Phy; Selected articles fr O.-W. Merten,D.

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From , Hemoglobin (VHb) to a Novel Class of Growth Stimulating Hemoglobin Proteinseria, yeast, mammals, and plants. The homodimeric hemoglobin of . (VHb) is the best characterized bacterial hemoglobin consisting of two identical 15.8 kDa subunits. The expression of VHb is up-regulated by oxygen limitation (hypoxia), but despite of intensive research activities, its physiological
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Protein Mass Production in Hybridomas and Recombinant CHO Cellsnt a heterodimeric protein encoded by two genes. We expressed antibodies in hybridomas as well as in recombinant CHO cells. Also other recombinant CHO cells were established under comparable conditions to express other glycoproteins encoded by single genes..Long-term (up to more than a year in cultu
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Translational Problems Associated with the Rare Arginine Codon CGG in ,lational problems when present in high numbers or in tandem in recombinant mRNA. The coding region for a N-terminal polyhistidine tagged Herpes Simplex Virus 2 (HSV2) protease contains 11 arginine CGG codons (3 tandem CGG codons occur near the C terminus of the protein) and should generate a protein
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