Titlebook: Recombinant Antibodies for Infectious Diseases; Theam Soon Lim Book 2017 Springer International Publishing AG, part of Springer Nature 201

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Engineering Antibodies for the Treatment of Infectious Diseases, The advancement of antibody engineering technologies has made it feasible to generate monoclonal antibodies. There are divergent methods for antibody engineering and optimization. In this chapter, we summarized the latest developments in engineering antibodies for infectious diseases.

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Computer-Aided Antibody Design: An Overview,to design molecules for optimizing affinity, better efficacy, greater safety and therapeutic function. Therefore, computational methods have become increasingly important to generate hypotheses, interpret and guide experimental works. In this chapter, we discussed the overall antibody design by computational approches.

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Advances in Experimental Medicine and Biologyhttp://image.papertrans.cn/r/image/824085.jpg

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https://doi.org/10.1007/978-3-319-72077-7Antibody Phage Display; Antibody Library; Synthetic Antibody; Immunized Antibody; Infectious Diseases; an

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Synthetic Antibodies in Infectious Disease,ombinant antibody library technology with an emphasis on our work using a highly successful synthetic single framework Fab library. We demonstrate its utility in targeting viruses and bacterial toxins in five case studies.

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