书目名称 | Receptor Tyrosine Kinases: Structure, Functions and Role in Human Disease | 编辑 | Deric L. Wheeler,Yosef Yarden | 视频video | | 概述 | Leading scientists and researcher providing cutting-edge data.A comprehensive resource that summarizes what we know about receptor tyrosine kinases.An incredible resource to researchers and clinicians | 图书封面 |  | 描述 | .Receptor Tyrosine Kinase: Structure, Functions and Role in Human Disease., for the first time, systematically covers the shared structural and functional features of the RTK family. Receptor Tyrosine Kinases (RTKs) play critical roles in embryogenesis, normal physiology and several diseases. And over the last decade they have become the .Number 1. targets of cancer drugs. To be able to conduct fundamental research or to attempt to develop pharmacological agents able to enhance or intercept them, it is essential first to understand the evolutionary origin of the 58 RTKs and their roles in invertebrates and in humans, as well as downstream signaling pathways. The assembly of chapters is written by experts and underscores commonalities between and among the RTKs. It is an ideal companion volume to .The Receptor Tyrosine Kinase: Families and Subfamilies., which proceeds, family by family through all of the specific subfamilies of RTKs, along with their unique landmarks.. | 出版日期 | Book 2015 | 关键词 | Kinase; Proteins; Receptors; Signaling pathways; Tyrosines | 版次 | 1 | doi | https://doi.org/10.1007/978-1-4939-2053-2 | isbn_softcover | 978-1-4939-4119-3 | isbn_ebook | 978-1-4939-2053-2 | copyright | Springer Science+Business Media New York 2015 |
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