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Titlebook: Recent Trends in Molecular Recognition; F. Diederich,H. Künzer Conference proceedings 1998 Springer-Verlag Berlin Heidelberg 1998 DNA.Nucl

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书目名称Recent Trends in Molecular Recognition
编辑F. Diederich,H. Künzer
视频video
丛书名称Ernst Schering Foundation Symposium Proceedings
图书封面Titlebook: Recent Trends in Molecular Recognition;  F. Diederich,H. Künzer Conference proceedings 1998 Springer-Verlag Berlin Heidelberg 1998 DNA.Nucl
描述Reasoning in terms of molecular recognition may be traced back to Emil Fischer, who practiced the art of chemistry at Humboldt University in Prussian Berlin a century ago. Today, it is clearly recognized that molecular recognition impacts and determines all life processes. It has become a key research field in both chemistry and biology and the emerging interface of what now is being called "chemical biology". The technological advances derived from this knowledge are particularly important, diverse, and directly evident in the pharmaceutical industry. Under the auspices of the Ernst Schering Research Foundation, a workshop held in Berlin in February 1998 addressed novel basic developments of potential relevance to drug research efforts. A balance of timely research topics in molecular recognition is presented in the lectures delivered by a multidisciplinary international panel of renowned scholars and documented in this volume.
出版日期Conference proceedings 1998
关键词DNA; Nucleotide; Oligosaccharid; biology; biomolecule; chemistry; drug; drug design; drug research; gene expr
版次1
doihttps://doi.org/10.1007/978-3-662-03574-0
isbn_softcover978-3-662-03576-4
isbn_ebook978-3-662-03574-0Series ISSN 0947-6075
issn_series 0947-6075
copyrightSpringer-Verlag Berlin Heidelberg 1998
The information of publication is updating

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Solid Phase Libraries of Glycopeptide Templates in the Study of Complex Oligosaccharide-Receptor Inng specificity through relatively weak additional interactions. Due to the nature of this interaction the specificity of selectin binding is quite broad (Kretzsch-mar et al. 1997). However, the high in vivo activity observed with selectin binding has yet to be explained.
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Designing Transition Metal Complexes for Molecular Recognition in Synthetic Transformations,o gain prominence in synthetic chemistry. Except for the obvious situation wherein enantiomerically pure starting materials, largely from nature, were the synthetic building blocks to permit access to enantiomerically pure products, the difficulties of controlling relative stereochemistry made the m
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Molecular and Dendritic Receptors for Small Biomolecules,l supramolecular assemblies in living systems. Studies of synthetic model systems complement biological investigations in contributing to the understanding of these processes and, at the same time, offer new mechanisms for controlling reactivity and specificity in chemistry (Lehn 1995). These fascin
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New Tools for Drug Design Based on Protein Ligand Recognition Principles,nked to a specific function (Lehn 1973). Molecular recognition is therefore binding that serves a particular purpose; it implies a structurally well-defined pattern of intermolecular interactions, requires appropriate shape complementarity, and is accordingly a question of information storage and re
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Solid Phase Libraries of Glycopeptide Templates in the Study of Complex Oligosaccharide-Receptor Inviruses, activation of the innate immune system, leukocyte rolling, hepatic clearing of aged serum proteins, and sorting of newly synthesized glycoproteins (Dwek 1996; Varki 1993). Based on their mode of binding they have been divided into three major groups. The E-, L-, and P-selectins and the gale
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