Titlebook: Recent Advances in Therapeutic Drug Monitoring and Clinical Toxicology; Seth Kwabena Amponsah,Yashwant V. Pathak Book 2022 The Editor(s) (

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Analytical Techniques for Therapeutic Drug Monitoring and Clinical Toxicology, seamless workflow. This chapter, thus, discusses the various high-throughput analytical techniques employed in TDM and CT, as well as the challenges associated with their respective applications as reported in the literature. It must be emphasized that consideration for a suitable analytical method

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Plasma Therapeutic Drug Monitoring and Clinical Toxicology,ell as age-related changes in drug metabolism, further complicates medication dosing. Therapeutic drug monitoring in the context of each patient serves to address these factors and requires collaboration between pharmacy, nursing, and medical teams.

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Dried Blood Spots in Therapeutic Drug Monitoring and Toxicology,evoted to discussing the implications of blood hematocrit variations (known as the hematocrit factor) and ways to tackle or cope with this pitfall. Finally, this chapter delineates the procedural steps in DBS sampling, recent innovations in DBS sampling, and high-throughput application of same.

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Reducing Toxicity in Critically Ill Patients by Using Therapeutic Drug Monitoring,inetic/pharmacodynamic (PK/PD) target selection, and dosage optimization procedures. The goal of this chapter is to examine available information on TDM practices for different drug classes and to illustrate how TDM might be useful in the reduction of toxicity in critically ill patients with serious

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