Titlebook: Recent Advances in Cellular and Molecular Aspects of Angiotensin Receptors; Mohan K. Raizada,M. Ian Phillips,Colin Sumners Book 1996 The E

创造性

Identification of AT1 Receptors on Cultured Astrocytes,ugh the control of water intake and sodium appetite, the secretion of ACTH and Vasopressin and the regulation of sympathetic tone (1). While high affinity binding sites for Ang II were initially characterized in brain homogenates (2, 3), the technique of . receptor autoradiography allowed visualizat

mortuary

Structure-Activity Relationship of the Agonist-Antagonist Transition on the Type 1 Angiotensin II Rpetitive analogues being compounds which can reversibly bind without producing any biological response to the receptor as well as competing with an agonist (e.g. Ang or other peptidic agonists) for the same site. Recently, a new concept was introduced that changes the classical view of agonist-antag

Conquest

Molecular Cloning and Expression of Angiotensin II Type 2 Receptor Gene, aldosterone release, peripheral norepinephrine release, cell proliferation and hypertrophy (1–3). These diversity of specific physiological effects of Ang II has suggested possible presence of subtypes of Ang II receptor. While the recognition of reducing agent-sensitive and -insensitive Ang II rec

强行引入

GIDDY

Molecular and Functional Characterization of Angiotensin II AT2 Receptor in Neuroblastoma N1E-115 C debate. Expression of AT2 receptors was detected in adrenals, uterus, ovary, heart, brain, and at highest levels in the developing fetus. This subtype has been associated with reduction of intracellular cGMP levels (3–5), modulation of tyrosine phosphorylation (4, 6–9), inhibition of a T-type calci

CAND

Characterization of The AT2 Receptor on Rat Ovarian Granulosa Cells, Most of the known physiological functions of Ang II are mediated by the AT. receptor. In contrast, the functional roles of the AT. receptor have not yet become apparent. The AT. receptor is widely distributed in adult tissues, whereas the AT. receptor exhibits widespread and abundant expression in

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flavonoids

Prostatism

Molecular Cloning and Expression of Angiotensin II Type 2 Receptor Gene,eptors had suggested the possibility of multiple subtypes (4), the question remained unresolved until the development of new peptide and non-peptidic antagonists of the Ang II receptor (5–7). These compounds turned out to be isoform specific and powerful tools for the characterization and isolation of the Ang II receptors and receptor genes.

Abbreviate

Regulation of Gene Transcription of Angiotensin II Receptor Subtypes in the Heart,ocardial infarction (2). The myocardium remote from the area of infarction is subjected to increased diastolic wall stress (2, 3), resulting in myocyte slippage (3) as well as myocyte hypertrophy (4). The myocardial hypertrophy exhibits characteristics of combined pressure and volume overload (4, 5).