书目名称 | Rational Drug Design | 副标题 | Methods and Protocol | 编辑 | Thomas Mavromoustakos,Tahsin F. Kellici | 视频video | | 概述 | Includes cutting-edge methods and protocols.Provides step-by-step detail essential for reproducible results.Contains key note and implementation advice from the expert | 丛书名称 | Methods in Molecular Biology | 图书封面 |  | 描述 | .This volume covers several aspects of rational drug design, such as synthesis of novel bioactive drugs; development and application of new methodologies; computational methods valuable for the establishment of new approaches in drug discovery; and the effects of physical-chemical and ADMET properties of the designed potential drugs. Chapters guide readers through amyloid deposits, Saturation Transfer Difference (STD) NMR, methods on bioguided design, the importance of lipophilicity in drug design, ADMET, FRET, structural biology, and homology modeling. Written in the highly successful .Methods in Molecular Biology .series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls..Authoritative and cutting-edge, .Rational Drug Design: Methods and Protocols. .aims to ensure successful results in the further study of this vital field.. | 出版日期 | Book 2018 | 关键词 | Intrinsically disordered proteins; GPCR targeting; Polypharmacology; Saturation Transfer Difference (ST | 版次 | 1 | doi | https://doi.org/10.1007/978-1-4939-8630-9 | isbn_softcover | 978-1-4939-9347-5 | isbn_ebook | 978-1-4939-8630-9Series ISSN 1064-3745 Series E-ISSN 1940-6029 | issn_series | 1064-3745 | copyright | Springer Science+Business Media, LLC, part of Springer Nature 2018 |
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