Titlebook: Randomised Controlled Clinical Trials; Christopher J. Bulpitt Book 1996Latest edition Springer Science+Business Media New York 1996 drugs.

折磨

Measurement of the Benefit : Risk Comparison, Cost-Effectiveness and Cost-Utility.,the same units as benefits and comprise increases in mortality and morbidity and a deterioration in QOL. Both benefit and risk should be expressed numerically as incidence, for example a 1% decrease in mortality from coronary heart disease/year to be compared with 0.01%/year increase in deaths from

Subjugate

Congestion

mastoid-bone

Different Trial Designs,concurrently (cross-over trial to detect an interaction). The remaining design variations do not involve a fixed number of persons being entered. The standard trial, cross-over trial, trial to detect an interaction between treatments, and cross-over trial to detect an interaction are illustrated in figure 5-1 for four treatments A, B, C, and D.

聚集

Information to be Collected During a Trial, defaulters and the attempts made to contact them. This chapter also considers the quantity of data to be collected, the design of documents, the questions to be asked, and the various stages of data preparation.

perpetual

有杂色

calumniate

The Evaluation of Subjective Well-Being and Measurement of Quality of Life,l. Only a few of the subjects may be expected to get the disease and in only a proportion of these may the preventive medicine be effective; yet adverse effects may affect all the subjects. In such a situation small risks may outweigh small gains and it is important to measure subjective well-being

泄露

MIR