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Titlebook: Randomised Controlled Clinical Trials; Christopher J. Bulpitt Book 1983 Springer Science+Business Media Dordrecht 1983 experiment

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发表于 2025-3-21 19:59:54 | 显示全部楼层 |阅读模式
书目名称Randomised Controlled Clinical Trials
编辑Christopher J. Bulpitt
视频video
丛书名称Developments in Biostatistics and Epidemiology
图书封面Titlebook: Randomised Controlled Clinical Trials;  Christopher J. Bulpitt Book 1983 Springer Science+Business Media Dordrecht 1983 experiment
描述Bradford Hill has defined a clinical trial as "A carefully and ethically designed experiment with the aim of answering some precisely framed question" [1]. This definition specifies a careful design and requires the provision of adequate controls. Random allocation of treatments to subjects is important to ensure is entitled that the treated and control groups are similar. Therefore this book Randomised Controlled Clinical Trials. We can define a randomised controlled trial by rewriting Bradford Hill‘s definition as follows, "A carefully and ethi­ cally designed experiment which includes the provision of adequate and ap­ propriate controls by a process of randomisation, so that precisely framed questions can be answered. " I am a firm advocate ofRandomised Controlled Clinical Trials but intend to give a balanced view of the advantages and disadvantages of these ethical experiments. This book is directed primarily at the medical research worker, although certain chapters may find a wider application. When discussing a randomised controlled trial, it is neither practicable nor desirable to divorce theory from practice, however the first ten chapters con­ centrate mainly on theory, an
出版日期Book 1983
关键词experiment
版次1
doihttps://doi.org/10.1007/978-1-4757-6358-4
isbn_softcover978-1-4757-6360-7
isbn_ebook978-1-4757-6358-4
copyrightSpringer Science+Business Media Dordrecht 1983
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书目名称Randomised Controlled Clinical Trials读者反馈学科排名




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Validity of the Results,esult but the interpretation of that result is incorrect. An incorrect interpretation can arise when the trial reveals a particular result and the investigator jumps to a further conclusion or when he decides that the same result will be true in different subjects.
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Writing the Protocol,and lastly supplying a permanent record of what was intended in the trial. The same document may serve all these functions, and in addition a section on finances may be included when the document is used as a grant application.
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Ethical Considerations,d wrong and a definition of how things are and not just how things should be [26]. Moreover, ethical problems concern the individual rather than the community. The community may benefit from the results of a trial but no individual should be asked to take an unreasonable risk to benefit the communit
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The Objectives of a Randomised Controlled Trial,ial to determine one major objective. For example, an investigator may be interested in a trial of a new antihypertensive drug in elderly patients. The major objective could be either to demonstrate the efficacy of the drug in lowering blood pressure or in preventing cardiovascular deaths. The first
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Validity of the Results,ecuted etc. as to have binding force” [55]. A trial result may not have binding force when executed incorrectly or when the trial provides a certain result but the interpretation of that result is incorrect. An incorrect interpretation can arise when the trial reveals a particular result and the inv
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