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Titlebook: Radiopharmaceuticals; A Guide to PET/CT an Ferdinando Calabria,Orazio Schillaci Book 2024Latest edition The Editor(s) (if applicable) and T

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Imaging Biomarkers of Neuroinflammations: TSPO Agents,tion (glucose metabolism), markers for pathological proteins (amyloid, tau, and synuclein aggregates), and also neuroinflammation, providing evidence for the pathophysiology in neurodegenerative diseases. The 18 kDa translocator protein (TSPO), also called peripheral benzodiazepine-binding site (PBR
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18F-FET,differential diagnosis between brain tumours recurrence and post-treatment changes. Furthermore, .F-FET PET may provide useful prognostic information in high-grade gliomas..Overall, based on literature data .F-FET PET may provide additional diagnostic information compared to standard MRI in neuro-oncology.
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Amyloid Imaging,needed to clarify the potential added value of these radiopharmaceuticals in evaluation of systemic or cardiac amyloidosis..Diagnostic pitfalls can be due to rapid washout of tracers in the brain, faint uptake in vascular dementia, or motion artifacts in PET/CT fusion imaging.
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64Cu-Radiopharmaceuticals,ccoli Asabella et al., Biomed Res Int. 2014:786463, 2014; Puig and Thiele, Curr Opin Chem Biol. 6:171–180, 2002). It may also play a role in cancer development and progression, acting as neo-angiogenetic promoter (Reilly and McAuslan, Adv Exp Med Biol 242:221–227, 1988; Finney et al., Clin Exp Pharmacol Physiol 36:88–94, 2009).
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PET Biomarkers for Tau Pathology,tial characteristics of tau accumulation during disease development, holding promise to serve as a highly valuable diagnostic tool in research and clinical settings. This chapter describes the current state of research employing tau biomarkers derived from neuroimaging with PET as well as recent technical developments in this field.
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18F-FES,e whole-body evaluation of recurrent ER-positive breast cancer in place of biopsy. Thus, it is a powerful diagnostic tool able to solve clinical dilemmas and provide systemic staging of breast cancer patients.
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Ferdinando Calabria,Andrea Cimini,Antonio Bagnato,Domenico Gullà,Giuseppe L. Cascini,Nicoletta Urban
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