书目名称 | Radiobiology of Glioblastoma | 副标题 | Recent Advances and | 编辑 | Luigi Pirtoli,Giovanni Luca Gravina,Antonio Giorda | 视频video | | 概述 | Provides the most recent and relevant advances in molecular radiobiology of glioblastoma, and the related possible changes in the clinical setting.Written by experts in the field.Bridges the gap of kn | 丛书名称 | Current Clinical Pathology | 图书封面 |  | 描述 | .This text properly considers the most recent and relevant advances in molecular RB of GB, taking into account the related topics of pathobiology, and underscores the most promising translational perspectives from the preclinical to the clinical domain. Section I (From Bedside to Bench) discusses conditions associated with RT resistance of GB and the consequent RB hints, technology improvements intended to overcome RT-resistance of GB, mathematical modeling of RB parameters from clinical studies, the present impact of molecular prognostic factors in therapy of GB, and RT tolerance of normal brain. Section II (Preclinical Research and Pathobiology Topics) presents the traditional and mechanistic/molecular approaches to RB of GB, genetic and epigenetic studies on GB, issues of cell-death pathways, stem-like cells, invasiveness, tumor microenvironment, hypoxia, mi-RNA manipulations, and nanoparticle technology. Section III (Translational Perspectives) presents RB issues related to molecular profiling and classification of GB as frames of reference for clinical studies, translational perspectives of gene therapy, evolving protocols based on pre-clinical data and large data-bases and on | 出版日期 | Book 2016 | 关键词 | Particle Radiation Therapy; Radiobiological Parameters; Tumor Initiation; Tumor Microenvironment; Gene T | 版次 | 1 | doi | https://doi.org/10.1007/978-3-319-28305-0 | isbn_softcover | 978-3-319-80321-0 | isbn_ebook | 978-3-319-28305-0Series ISSN 2197-781X Series E-ISSN 2197-7828 | issn_series | 2197-781X | copyright | Springer International Publishing Switzerland 2016 |
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