Titlebook: Radiobiology Textbook; Sarah Baatout Textbook‘‘‘‘‘‘‘‘ 2023 The Editor(s) (if applicable) and The Author(s) 2023 radiation physics and chem

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nocturia

History of Radiation Biology, linear no-threshold (LNT) risk model considers that cancer risk is proportional to radiation dose and no radiation exposure is safe. Although LNT has never been scientifically validated, it is used for the management of radiological protection. Progress in understanding the carcinogenesis associate

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Mechanistic, Modeling, and Dosimetric Radiation Biology,s. Finally, the link between energy deposition events and detectable biological effects (from the molecular to the organism level) is investigated using Monte Carlo simulation codes and macroscopic radiobiological models.

INCUR

Clinical Radiobiology for Radiation Oncology,is provided on tumor characteristics, for example, tumor type, growth kinetics, hypoxia, aberrant molecular signaling pathways, cancer stem cells and their impact on the response to RT. The role of the tumor microenvironment and microbiota is described and the effects of radiation on the immune syst

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Radiobiology of Combining Radiotherapy with Other Cancer Treatment Modalities,allowing the healthy, normal tissues and organs to be spared while maintaining the antitumor effect. Spatial fractionation of radiation in tumor therapy, another method that reduces damage to normal tissue is presented. Normal tissue doses could also be minimized by interstitial or intraluminal irra

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Radiobiology of Accidental, Public, and Occupational Exposures, of individuals are exposed such that triage is required to quickly identify those needing medical intervention to mitigate ARS. Strategies for triage for treatment are described with respect to trauma, contamination, and exposure along with a discussion of suggested countermeasures for internal exp

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Space Radiobiology, sections of this chapter are dedicated to the vast research that has been developed through the years concerning space radiation biology, from small animals to plant models and 3D cell cultures, the use of extremophiles in the study of radiation resistance mechanisms to the importance of ground-bas

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Radioprotectors, Radiomitigators, and Radiosensitizers,ge and ROS production, increasing IR toxicity on tumor cells, thus they are used to increase radiotherapy efficacy in cancer patients. The section “Radionuclides and methods to treat contaminated individuals” describes the medical consequences and treatment modalities of internal contamination by ra