Titlebook: Radioactive Isotopes in Clinical Medicine and Research XXIII; Helmar Bergmann,Horst Köhn,Helmut Sinzinger Conference proceedings 1999 Spri

motivate

The Development of Chromatographic 188W/188Re Generators for Therapy) have been investigated. The obtained values of capacity varied from 1,5 to 75 mg/g adsorbent. Several rhenium-188 generators based on alumina and zir-conium(IV) oxide were loaded with 370–1110 MBq high specific activity .W. Carrier-free .Re was eluted as sodium perrhenate with normal saline (3–17

笼子

Evaluation of mRNA Targeting by Labeled Oligonucleotides for Tumor-Diagnosisd mRNA based on Watson-Crick base pairing. As cancer model for follicular non-Hodgkin lymphomas an adjustable Bcl-2 expression system, which can produce Bcl-2 mRNA in high amounts, was chosen. A series of oligonucleotides was evaluated with this test cell line.

parallelism

Synthesis and Evaluation of [123I]Iodoaminoglutethimide, a Ligand for Visualization of the Aromataseme complex by SPECT is described. 1-123 IAG was synthesized by electrophilic substitution of aminoglutethimide with n.c.a. [.I]NaI. High specific activities were obtained (315 Gbq/mg-8.5Ci/mg). Biodistribution studies with female NMRI mice were undertaken. High accumulation of radioactivity in liver

STIT

Comparative Analysis of Kinetic Models to Study Glucose Metabolism of the Brain0–25) of volumes of interest (VOI) were defined on the PET images. Data of the kinetic studies belonging to these VOI-s were evaluated using the standard uptake value (SUV) method, or calculating glucose metabolic rate (GMR) applying Patlak analysis (PA); and three-compartment model with nonlinear r

DEAWL

一回合

Comparison of Iodine-123 Labelled Nor-β-CIT and β-CIT as Potential Radioligands for Serotonin Transpe of tracer in the brain (6 %/ID at 30 min). Highest uptake was observed in the striatum, the thalamus and in the mid-brain. The specific binding of [.I]nor-βCIT in the mid-brain was 20 % higher than that of [.I]β-CIT. The high radioactivity in the mid-brain is assumed to represent the accumulation of [.I]nor-β-CIT in the serotonin transporter.

比目鱼

Radioimmunotherapy of Colorectal Cancer in Small Volume Disease: Preclinical Evaluation in Comparisoe a viable therapeutic option in colorectal cancer patients with limited disease. Myelotoxicity is the only dose-limiting organ toxicity. Although most patients were treated below the maximum tolerated dose, encouraging anti-tumor effects have been observed.

IDEAS

I-131-Lipiodol Therapy in Liver Neoplasmsts with big tumor mass, 5 (4 HCC, 1 CCC) had stable disease, and 2 HCC were progressive. 1 patient died. The BCM proved significant reduction in number and size. 18-FDG-PET and CT controls showed in part different results with pretherapeutic PET proving high interindividual variability in tumor activity. Side effects were tolerabel.

aggressor

TOXIN