Titlebook: Rabies in Man and Animals; Sudhi Ranjan Garg Book 2014 Springer India 2014 Animal bite.Dog bite.Hydrophobia.Lyssavirus.antibacterial drug

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Book 2014bies, misconceptions in the community about the disease and unsystematic approach for its preventionand control are also responsible for the grim situation. Targets have been set for elimination of human and dog rabies in all Latin American countries by 2015 and of human rabies transmitted by dogs i

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Introduction,ed animals. The disease is transmitted from animal to animal and from animal to man through saliva. Despite being vaccine preventable, rabies kills more than 55,000 people worldwide every year apart from causing huge loss of domestic animals. Most human rabies deaths occur in Asia and Africa; India

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Causation of Disease, for classical rabies that constitutes a vast majority of rabies cases. Other lyssaviruses appear to have more restricted geographical and host range. All species of mammals are susceptible but only a few species are important as major reservoirs. The virus is transmitted between mammals usually thr

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Epidemiology,Rabies is maintained in two epidemiological cycles, urban cycle and sylvatic cycle. Dogs are the main reservoir hosts in the urban cycle which predominates in India and many other developing countries in Asia, Africa, and Central and South America. Sylvatic cycle is predominant in Europe and North A

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Rabies Manifestations and Diagnosis, The animals may exhibit furious form of the disease or dumb/paralytic form. In general, rabies virus causes acute encephalitis with fatal outcome. The incubation period of rabies is quite variable in different cases as it is influenced by several factors. In humans, it is generally 1–3 months but m

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Risk Assessment and Management of Exposures,e prophylaxis (PEP) requirements. The World Health Organization has laid down guidelines for differentiating the categories of potential rabies exposure and taking appropriate prophylactic measures. Development of a decision tree assists in risk evaluation. A three-pronged strategy is adopted to man

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Vaccines and Other Biologicals,e at Central Research Institute in Kasauli (India). With the advent of modern cell culture vaccines, the WHO does not advocate the use of the earlier nerve tissue vaccines anymore. Modern vaccines produced on various cellular substrates and continuous cell lines are highly effective in both pre-expo

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