Titlebook: RNA and Cancer; Jane Y. Wu Book 2013 Springer-Verlag Berlin Heidelberg 2013 Alternative splicing.Cell death.Imaging.Microarray.Tumor

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的阐明

Jane Y. WuReview of the most current advances in the understanding of post-transcriptional gene regulation.Special focus on RNA processing and its role in cancer development and treatment.Written by internation

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Cancer Treatment and Researchhttp://image.papertrans.cn/r/image/820209.jpg

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Parallel

978-3-642-44485-2Springer-Verlag Berlin Heidelberg 2013

Concomitant

RNA and Cancer978-3-642-31659-3Series ISSN 0927-3042 Series E-ISSN 2509-8497

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Coupling Between Transcription and Alternative Splicing, more than one way. Introns are efficiently removed while transcripts are still being synthesized, supporting the idea of a co-transcriptional regulation of alternative splicing. Evidence of a functional coupling between splicing and transcription has recently emerged as it was observed that propert

焦虑

Detection of Alternatively Spliced or Processed RNAs in Cancer Using Oligonucleotide Microarray,and management. DNA microarrays have been used to measure changes in mRNA or microRNA level, but less often the change of RNA isoforms. Here we appraise the utilization of microarray in detecting alternatively processed RNAs, which have alternative splice forms, retained introns, or altered 3′ untra

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Cancer-Associated Perturbations in Alternative Pre-messenger RNA Splicing,nctional messenger RNAs (mRNAs). Alternative splicing of a single pre-mRNA results in the production of different mRNAs. Although complex organisms use alternative splicing to expand protein function and phenotypic diversity, patterns of alternative splicing are often altered in cancer cells. Altern

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Alternative Splicing of Tumor Suppressors and Oncogenes,is now ample evidence that alternative splicing errors, caused by mutations in .-acting elements and defects and/or imbalances in .-acting factors, may be causatively associated to cancer progression. Recent work indicates the existence of an intricate network of interactions between alternative spl