Titlebook: RNA Structure and Function; Jan Barciszewski Book 2023 The Editor(s) (if applicable) and The Author(s), under exclusive license to Springe

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A Moveable Feast. Molecular Modeling and Simulation Unraveling Cross-Talks Between RNA Structure anc equilibrium assumed by RNA sequences, either cellular or viral. After pointing out the role played by specific RNA structures in regulating key biological functions, or in assuring either viral replication or immune system activation, we will show how computationally efficient multiscale approache

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The Hidden Layer of RNA Variants,ed by RNA surveillance and quality control systems. Nuclear RNA degradation pathways play important roles in these systems and in shaping the transcriptome and preventing diseases. In this review, we summarize current knowledge of nuclear noncoding RNAs. We then discuss nuclear RNA degradation facto

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Functional Role of Non-coding RNAs in Prostate Cancer: From Biomarker to Therapeutic Targets,standard and novel therapies. This acquired resistance is a multifactorial problem involving the interplay of several genetic and epigenetic alterations that contribute significantly to the growth, invasiveness, and metastasis of CaP. A deeper understanding may lead to novel therapeutic intervention

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Methods to Analyze Post-transcriptional Modifications Applied to Stable RNAs in ,proaches, and cryo-EM structural analysis that are used to detect and localize the modifications in tRNAs and rRNAs. We illustrate how the combination of methods was necessary to avoid technical biases for a successful mapping of the modifications in tRNAs and rRNAs in ..