Titlebook: RNA Processing; Disease and Genome-w Gene W. Yeo Book 2016 The Editor(s) (if applicable) and The Author(s), under exclusive license to Spri

词汇记忆方法

Regulation of Tissue-Specific Alternative Splicing: , as a Model System,his chapter, we highlight key concepts and outstanding goals in studies of tissue and cell-specific alternative splicing. We place particular emphasis on the use of . as a tractable model organism for . studies of alternative splicing between tissues and also at single cell resolution. We describe o

NOVA

RNA Granules and Diseases: A Case Study of Stress Granules in ALS and FTLD,an example, we discuss the principles of RNA granule formation, which rely on the multivalency of RNA and multi-domain proteins as well as low-affinity interactions between proteins with prion-like/low-complexity domains (e.g. FUS and TDP-43). We then explore how dysregulation of RNA granule formati

stress-test

Post-Translational Modifications and RNA-Binding Proteins,cidate the roles of a handful of RNA-binding proteins and their effect on RNA metabolism, the progress of studies to understand the effects of post-translational modifications of this class of proteins is far from complete. This chapter summarizes the work that has been done to identify the conseque

OUTRE

example of some recent European procedures. The author emphasizes the idea that e-Justice is made up of . at the service of Justice, amongst which are included electronic communications: but those tools should never dictate the development of the purpose they serve and it would also be intolerable t

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拥挤前

案发地点

Tomas J. Bos,Julia K. Nussbacher,Stefan Aigner,Gene W. Yeo state consists of the ferrous ion and a collectively oxidized set of ligands. The presence of a ‘hole’ on the ligands decreases the probability that the Fe(II) site will exhibit typically ferrous behavior as regards metal-ligand vibrational frequency, etc. Much of the earlier data must be regarded

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engrossed

Tethered Function Assays as Tools to Elucidate the Molecular Roles of RNA-Binding Proteins,thering systems. We illustrate specific examples of the application of the assay in elucidating the function of various classes of RBPs. We also discuss how classic tethering assay approaches and insights gained from them have been empowered by more recent technological advances, including efficient

破布