书目名称 | RNA Interference | 副标题 | From Biology to Clin | 编辑 | Wei-Ping Min,Thomas Ichim | 视频video | | 概述 | Provides a global overview of the state-of-the-art in RNA interference and practical details used experimentally in modern day experiments.Deciphers, organizes, and explains the myriad of techniques u | 丛书名称 | Methods in Molecular Biology | 图书封面 |  | 描述 | .From the early days when RNA interference was a strange artifact in worms to the 2006 Noble Prize received by Fire and Mello and the current clinical trials, the field of RNA interference has grown at a breakneck pace. In .RNA Interference: From Biology to Clinical Applications., expert contributors provide an overview of the most current science and protocols that span the biological disciplines from detailed nucleic acid chemistry, to pharmacology, to the manipulation of signal transduction pathways. Divided into three distinct sections, this volume delves into the physiology of RNA interference, RNA interference in the laboratory and siRNA delivery, and preclinical and clinical issues associated with the use of RNAi-inducing agents as drugs in order to stimulate new questions and offer the tools necessary to start addressing those questions. Written in the highly successful .Methods in Molecular Biology.™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls...Authoritative and inspiring, .RNA Interf | 出版日期 | Book 2010 | 关键词 | Gene silencing; Laboratory; RNAi-inducing agents; Therapeutics and drugs; Viral defense; physiology; siRNA | 版次 | 1 | doi | https://doi.org/10.1007/978-1-60761-588-0 | isbn_softcover | 978-1-4939-6134-4 | isbn_ebook | 978-1-60761-588-0Series ISSN 1064-3745 Series E-ISSN 1940-6029 | issn_series | 1064-3745 | copyright | Springer Science+Business Media, LLC 2010 |
The information of publication is updating
|
|