书目名称 | RNA Folding | 副标题 | Methods and Protocol | 编辑 | Ronny Lorenz | 视频video | | 概述 | Includes cutting-edge methods and protocols.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from the experts | 丛书名称 | Methods in Molecular Biology | 图书封面 |  | 描述 | .To understand and predict the behavior and function of RNAs, sophisticated tools are required to simulate and analyze their potential for forming structures. This volume discusses the various levels of prediction and algorithmic approaches to RNA folding. The chapters in this book cover topics such as energy parameters of the nearest-neighbor (NN) energy model; classified dynamic programming to address exponential growth of candidate structures that an RNA molecule may fold into; sequence evolution and conserved structures among multiple RNA sequences; the latest framework capable of handling both positive and negative RNA sequence design objectives; and kinetic folding approaches that look at the dynamic nature of RNA folding. Written in the highly successful .Methods in Molecular Biology .series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.. . Cutting-edge and comprehensive, .RNA Folding: Methods and Protocols. is a valuable resource for researchers who are interested in learning more about this impo | 出版日期 | Book 2024 | 关键词 | Structure Prediction; Pseudoknots; Dynamic Programming; Folding Dynamics; RNApuzzles Experiment | 版次 | 1 | doi | https://doi.org/10.1007/978-1-0716-3519-3 | isbn_softcover | 978-1-0716-3521-6 | isbn_ebook | 978-1-0716-3519-3Series ISSN 1064-3745 Series E-ISSN 1940-6029 | issn_series | 1064-3745 | copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines |
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