Titlebook: RNA Design; Methods and Protocol Alexander Churkin,Danny Barash Book 2025 The Editor(s) (if applicable) and The Author(s), under exclusive

自由才谨慎

书目名称RNA Design影响因子(影响力)




书目名称RNA Design影响因子(影响力)学科排名




书目名称RNA Design网络公开度




书目名称RNA Design网络公开度学科排名




书目名称RNA Design被引频次




书目名称RNA Design被引频次学科排名




书目名称RNA Design年度引用




书目名称RNA Design年度引用学科排名




书目名称RNA Design读者反馈




书目名称RNA Design读者反馈学科排名

tolerance

1064-3745 e laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls... ..Authoritative and cutting-edge, .RNA Design: Methods and Protocols .aims to ensure successful results in the further study of this vital field..978-1-0716-4081-4978-1-0716-4079-1Series ISSN 1064-3745 Series E-ISSN 1940-6029

灾祸

Sequence Design Using RNAstructure, is that objective functions need to consider the folding ensemble of RNA molecules to avoid off target structures. In this chapter, we provide protocols for two software tools from the RNAstructure package: “Design” for structured RNA sequence design and “orega” for unstructured RNA sequence design.

否认

不规则的跳动

SHAPE Probing to Screen Computationally Designed RNA,n addition, it necessitates the analysis and evaluation of many experimental results that may reveal to be very tedious. Here we propose an experimental and analytical workflow that eases the screening of thousands of designed RNA sequences at once. In particular, we have developed . a customized software suite available at ..

Merited

buoyant

Datasets for Benchmarking RNA Design Algorithms,asets to assess these programs. Here, we present a large dataset of internal and multibranched loops extracted from PDB-deposited RNA structures that encompass a wide spectrum of design difficulties. Furthermore, we conducted benchmarking tests of widely utilized open-source RNA design algorithms employing this dataset.

calamity

Machine Learning for RNA Design: LEARNA,ncepts of reinforcement learning and its extension, automated reinforcement learning, and outline how these concepts can be successfully applied to the design of RNAs. The chapter is structured to guide through the usage of the different programs with explicit examples, highlighting particular applications of the individual tools.

Soliloquy

Simulated Annealing for RNA Design with SIMARD,oblem and approached with simple heuristics. The main focus of this paper is to describe an RNA design algorithm based on simulated annealing. Additionally, noteworthy features and results will be presented herein.

弄污