| 书目名称 | RAS Family GTPases | | 编辑 | Channing Der | | 视频video | | | 概述 | Focuses on one of the most intensely studied proteins and areas in cell biology.Establishes many of our current paradigms in the signalling circuitry of a cell.Of interest to researchers in a diverse | | 丛书名称 | Proteins and Cell Regulation | | 图书封面 |  | | 描述 | .Since 1982, Ras proteins have been the subject of intense research investigation by the biomedical research community. The wide interest in Ras has been stimulated for three key reasons...First, their frequent mutational activation in human cancers establishes Ras proteins as important mediators of oncogenesis and targets for anti-cancer drug discovery. Second, Ras proteins act as signalling nodes activated by diverse extracellular stimuli, and activated Ras in turn regulates a diversity of cytoplasmic signalling networks. Third, Ras proteins are founding members of a large superfamily of Ras-related small GTPases. Over 150 Ras-related small GTPases are found in the human genome, with orthologs found in all vertebrate species and invertebrates...This book features chapters by leading investigators in the field that highlight the current state-of-the art in Ras biochemistry, structure and biology. This book is an excellent reference for students in the biomedical sciences and for investigators in the field.. | | 出版日期 | Book 2006 | | 关键词 | Activation; Endoplasmatisches Reticulum; biochemistry; cells; influence; proteins; saccharomyces cerevisia | | 版次 | 1 | | doi | https://doi.org/10.1007/1-4020-4708-8 | | isbn_softcover | 978-90-481-7110-1 | | isbn_ebook | 978-1-4020-4708-4Series ISSN 1567-2530 Series E-ISSN 2542-9973 | | issn_series | 1567-2530 | | copyright | Springer Science+Business Media B.V. 2006 |
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发表于 2025-3-21 16:24:33
