书目名称 | Quorum Sensing vs Quorum Quenching: A Battle with No End in Sight | 编辑 | Vipin Chandra Kalia | 视频video | | 概述 | Defines quorum sensing (QS) systems as the global regulators of bacterial genes expression.Discusses the potential of QS regulation as a new drug target for the treatment of bacterial infections.Addre | 图书封面 |  | 描述 | Microbial relationships with all life forms can be as free living, symbiotic or pathogenic. Human beings harbor 10 times more microbial cells than their own. Bacteria are found on the skin surface, in the gut and other body parts. Bacteria causing diseases are the most worrisome. Most of the infectious diseases are caused by bacterial pathogens with an ability to form biofilm. Bacteria within the biofilm are up to 1000 times more resistant to antibiotics. This has taken a more serious turn with the evolution of multiple drug resistant bacteria. Health Departments are making efforts to reduce high mortality and morbidity in man caused by them. Bacterial Quorum sensing (QS), a cell density dependent phenomenon is responsible for a wide range of expressions such as pathogenesis, biofilm formation, competence, sporulation, nitrogen fixation, etc. Majority of these organisms that are important for medical, agriculture, aquaculture, water treatment and remediation, archaeological departments are: Aeromonas, Acinetobacter, Bacillus, Clostridia, Enterococcus, Pseudomonas, Vibrio and Yersinia spp. Biosensors and models have been developed to detect QS systems. Strategies for inhibiting QS s | 出版日期 | Book 2015 | 关键词 | Antibacterial agents; Antipathogenic drugs; Biofilm; Biosensors; Pathogenic bacteria; gene expression | 版次 | 1 | doi | https://doi.org/10.1007/978-81-322-1982-8 | isbn_softcover | 978-81-322-3548-4 | isbn_ebook | 978-81-322-1982-8 | copyright | Springer India 2015 |
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