Titlebook: Quasispecies: Concept and Implications for Virology; Esteban Domingo Book 2006 The Editor(s) (if applicable) and The Author(s), under excl

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Transitions in Understanding of RNA Viruses: A Historical Perspective,es demonstrate that they form RNA quasispecies populations; the most rapidly mutating, highly variable and genetically versatile life forms on earth. Their enormous populations, rapid replication and extreme genetic plasticity can allow rates of evolution that exceed those of their eukaryotic host p

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Molecular Mechanisms of Poliovirus Variation and Evolution,ments (e.g., deletions, insertions and recombination). After description of basic mechanisms underlying this variability, the review focuses on regularities of poliovirus evolution (mutation fixation) in tissue cultures, human organisms and populations.

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0070-217X rus replications are intimately related to viral disease mechanisms. The central topics of this volume are the origins of the quasispecies concept, and the implications of quasispecies dynamics for viral populations.978-3-642-06582-8978-3-540-26397-5Series ISSN 0070-217X Series E-ISSN 2196-9965

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珠宝

Mutant Clouds and Occupation of Sequence Space in Plant RNA Viruses,ividual quasispecies level. Many questions about the nature of plant RNA virus populations and factors that affect the effective population sizes, such as genetic bottlenecks and postive and negative selection, have only begun to be studied. Many more analyses are required before generalized patterns can be determined.

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与野兽博斗者

Arenavirus Diversity and Evolution: Quasispecies In Vivo,enavirus, indicates to what extent a quasispecies dynamics may play a role in arenavirus adaptability and pathogenesis. Several aspects of arenavirus variability and its contribution to pathogenesis will be discussed.