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Titlebook: Quantitative Neurophysiology; Joseph V. Tranquillo Book 2009 Springer Nature Switzerland AG 2009

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Passive Membranes,body can be characterized by their electrical properties, the nervous and muscular system in particular use electrical impulses to communicate information between cells. In this chapter, we will explore the basic principles of cellular electrophysiology which may be applied to any cell in the body.
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Active Membranes,d . was modeled as a simple resistor and battery in series. In this chapter, we consider what happens when a stimulus causes . to reach threshold. The result is that . no longer behaves linearly. The nonlinearity of the membrane is represented in a circuit model as the . in Fig. 3.1.
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Propagation,patch of membrane to the next, and so on, around the cell. Likewise, electrical impulses spread down dendrites to the soma by moving from one patch of membrane to the next. A similar process is involved in the spread of electrical impulses from the axon hillock down the axon. These waves of electric
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Synapses,t of the action, however, occurs at the connections between neurons. There are two primary ways that neurons connect. First are . which are proteins that directly connect the intracellular space of two neurons. Typically, gap junctions are modeled as a linear resistor.
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Networks of Neurons,e that it is the complex connections and interactions between neurons that give rise to the enormous range of functions and behaviors of the brain. The first half of this chapter will focus largely on the work of Roger Traub’s research group on simulating thousands of multicompartment neurons. The s
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Extracellular Recording and Stimulation,trivial and nearly impossible in the clinic. Therefore, in most situations, it is an extracellular potential that is recorded. In this chapter we will use Maxwell’s equations to derive a relationship between extracellular potentials and membrane currents.
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