Titlebook: Quantitative Methods in Supply Chain Management; Models and Algorithm Ioannis T. Christou Book 2012 Springer-Verlag London Limited 2012 Dec

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Book 2012nistic and stochastic models for inventory control with a detailed analysis on periodic review systems and algorithmic development for optimal control of such systems. The fifth chapter discusses models and algorithms for location/allocation problems arising in supply chain management, and transport

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downwards depending on the therapeutic requirement. Definitions of the morphological characteristics, surface properties, and polymorphic structures will also be given, emphasizing their influence on the incorporation parameters of the API, such as yield of production, loading capacity, and encapsu

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Ioannis T. Christou and molecular levels. With a deeper understanding of these physiological bases, further advances have been introduced by DDSs endowed with target-specific and bioadhesive properties to various sites in the body to reduce the side effects and enhance the bioavailability of drugs at the diseased site

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Ioannis T. Christouimproving or maintaining visual acuity in CNV patients over long periods of time. The work on the new generation of anti-VEGF agents with higher potency and long-lasting efficacy is ongoing with the goal of reducing the frequency of intravitreal injections required for achieving good visual acuity o

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Ioannis T. Christouloped and investigated for the improved delivery of drugs to the brain disorders. The effective delivery and penetration across the endothelial cells of brain can be achieved by considering various physiochemical factors of nanoparticles and of drugs while designing and formulation development. Addi

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Ioannis T. Christouators have also proven their efficacy in Alzheimer’s treatment. Such neuromodulators can be advantageous for the early staging of AD. Although various neuroprotective medicaments are available for the management of AD, but their efficacy is limited due to blood-brain barrier obstruction, high lipoph

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Ioannis T. Christouloped and investigated for the improved delivery of drugs to the brain disorders. The effective delivery and penetration across the endothelial cells of brain can be achieved by considering various physiochemical factors of nanoparticles and of drugs while designing and formulation development. Addi

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o bypass the blood–brain barrier to reach the central nervous system. The presented chapter highlights the method of intranasal delivery in mice using chitosan–siRNA nanoparticle formulation, under mild anesthesia and the identification of successful siRNA delivery in the brain tissues, through hist