书目名称 | Quantitative Health Risk Analysis Methods |
副标题 | Modeling the Human H |
编辑 | Louis Anthony Cox |
视频video | |
概述 | A thorough analytical treatment and exposition of some of the main quantitative methods that can be used to assess the risk of human health consequences of using antibiotics in food animals. The ‘prob |
丛书名称 | International Series in Operations Research & Management Science |
图书封面 |  |
描述 | This book grew out of an effort to salvage a potentially useful idea for greatly simplifying traditional quantitative risk assessments of the human health consequences of using antibiotics in food animals. In 2001, the United States FDA’s Center for Veterinary Medicine (CVM) (FDA-CVM, 2001) published a risk assessment model for potential adverse human health consequences of using a certain class of antibiotics, fluoroquinolones, to treat flocks of chickens with fatal respiratory disease caused by infectious bacteria. CVM’s concern was that fluoroquinolones are also used in human medicine, raising the possibility that fluoroquinolone-resistant strains of bacteria selected by use of fluoroquinolones in chickens might infect humans and then prove resistant to treatment with human medicines in the same class of antibiotics, such as ciprofloxacin. As a foundation for its risk assessment model, CVM proposed a dramatically simple approach that skipped many of the steps in traditional risk assessment. The basic idea was to assume that human health risks were directly proportional to some suitably defined exposure metric. In symbols: Risk = K × Exposure, where “Exposure” would be defined in |
出版日期 | Book 2006 |
关键词 | Analysis; Animals; Antibiotics; Assessment; Cox; Food; Health; Mycin; Operations Research; Quantitative; Radio |
版次 | 1 |
doi | https://doi.org/10.1007/b136472 |
isbn_softcover | 978-1-4419-3850-3 |
isbn_ebook | 978-0-387-26118-8Series ISSN 0884-8289 Series E-ISSN 2214-7934 |
issn_series | 0884-8289 |
copyright | Springer-Verlag US 2006 |