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Titlebook: QSAR in Environmental Toxicology - II; Proceedings of the 2 Klaus L. E. Kaiser Conference proceedings 1987 D. Reidel Publishing Company, Do

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Factors Determining Partitioning of Hydrophobic Organic Chemicals in Aquatic Organisms,ir relative importance. It is concluded that, although insufficient experimental data presently exist which can conclusively establish the cause(s), reduced lipid solubility and reduced bioavailability are the most likely factors contributing to the loss of linear correlation for non-metabolizing chemicals.
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A Discussion of Correlations for Narcosis in Aquatic Species, in the target phase. If this hypothesis is accepted, it becomes possible to estimate and correlate target/octanol and target/water partition coefficients. Novel methods of presenting quantitative structure-activity relationships (QSARs) based on these partition coefficients are suggested. The hypot
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Structure/Environmental Fate Relationships,ds of chemicals. Essential parts of the system are models which describe transport and transformation of chemicals in various environmental media. The models allow for estimating appropriate descriptors of mobility, accumulation and persistence on the base of the substances’ physico-chemical propert
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Bioaccumulaton of Phenols in Zebrafish Determined by a Dynamic Flow Through Test,, 3-chlorophenol, 4-bromophenol, 2,4-dinitro-6-methylphenol, 3,5-dibromo-4- cyanophenol, 4-tert-butylphenol, 2,4,6-tribromophenol, 2,4-dinitro-6-sec- butylphenol, 2,4-dinitro-6-tert-butylphenol, and pentachlorophenol. Biocon- centration factors (BCFs) for zebrafish (.) were calculated from the kinet
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Tissue Distribution and Elimination of 1,2,3,4-, 1,2,3,5- and 1,2,4,5-Tetrachlorobenzene in the Rate tetrachlorobenzenes were rapidly absorbed and distributed in all tissues examined after oral administration; the highest concentrations were found in the fat, liver, skin and adrenal gland. Of the three isomers, tissues of 1,2,4,5- tetrachlorobenzene treated rats had the highest radioactivity meas
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Assessing the Administrative Utility of the ,, administratively useful to the regulatory agencies involved in implementing the Canadian .. This is done by analyzing how the system’s properties relieve the pressures exerted by three limiting factors in the Act: 1) costs and delays, 2) the criterion of acceptable risk, and 3) the administrative h
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Correlation of Biodegradability with Atomic Charge Difference and Superdelocalizability,neric series of compounds. For different congeneric series, the regression coefficients and intercepts of the correlation equations are very similar, so that the equations can be combined. Hence for 112 compounds comprising alcohols, phenols, ketones, carboxylic acids, ethers and sulfonates, we obta
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