| 书目名称 | Purinergic Regulation of Respiratory Diseases |
| 编辑 | Maryse Picher,Richard C. Boucher |
| 视频video | |
| 概述 | Pivotal Roles of Purinergic Signaling in Airway Defenses.Disease-Specific Aberrances in Sputum Adenosine Regulation.Diagnostic Value of AMP-Mediated Bronchoconstriction.Distinct Therapies for Acute Lu |
| 丛书名称 | Subcellular Biochemistry |
| 图书封面 |  |
| 描述 | We proudly present the first book to integrate all aspects of purinergic signaling in the respiratory system. The first chapters introduce basic notions of purinergic pharmacology and metabolism, which allows readers from all scientific backgrounds to fully grasp the importance of these signaling networks for airway defenses, including mucociliary clearance and inflammatory responses. Then, chapters are devoted to the groundbreaking discovery that chronic respiratory diseases, including asthma, cystic fibrosis and chronic obstructive pulmonary disease (COPD), present specific aberrances in purinergic signaling which essentially drive lung complications. The last chapters describe the animal models used to investigate purinergic signaling in respiratory diseases, and the therapeutic applications developed by the pharmaceutical industry based on receptor agonists/antagonists and metabolic correctors. This highly comprehensive manuscript constitutes an invaluable tool for beginners and experts to follow the rapidly evolving research field of purinergic signaling. Furthermore, the critical analysis of past clinical protocols should facilitate the identification of potent therapeutic ta |
| 出版日期 | Book 2011 |
| 关键词 | Adenosine; Asthma; Chronic obstructive pulmonary disease (COPD); Ectonucleotidases; Purinergic signaling |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-94-007-1217-1 |
| isbn_softcover | 978-94-007-3606-1 |
| isbn_ebook | 978-94-007-1217-1Series ISSN 0306-0225 Series E-ISSN 2542-8810 |
| issn_series | 0306-0225 |
| copyright | Springer Science+Business Media B.V. 2011 |
发表于 2025-3-21 19:48:42
