| 书目名称 | Purinergic Receptors and their Modulators |
| 编辑 | Vittoria Colotta,Claudiu T. Supuran |
| 视频video | |
| 概述 | Discusses role of purinergic signalling in pathophysiological processes.Overviews purinergic receptors and their modulators.Highlights current perspectives and future challenges |
| 丛书名称 | Topics in Medicinal Chemistry |
| 图书封面 |  |
| 描述 | .This book overviews purinergic receptors that are playing key roles in human and pathophysiological processes. The book elaborates on how selective P1 and P2 modulators have been developed as therapeutics for a variety of diseases. It also provides an overview of current perspectives in the design of purinergic receptor modulators and future challenges such as the availability of selective ligands for all receptor subtypes..Divided into 12 chapters, this comprehensive volume also offers a multidisciplinary perspective on the historical evolution, starting with a chapter devoted to the roots and early discoveries of adenosine and its receptors, followed by a twenty-year retrospective on the synthesis, properties, and functional potential of adenosine receptor ligands, probes, and functional conjugates. In the next chapters, experts in the field delve into topics such as the therapeutic potential of adenosine receptor ligands in wound healing and fibrosis, the therapeutic benefits of A2A receptor antagonists, the A2B adenosine receptor as a target for brain ischemia or demyelination, the development and latest advancements in clinical trials of A3 adenosine receptor ligands. Other c |
| 出版日期 | Book 2023 |
| 关键词 | CD73 inhibitors; A3 adenosine receptor ligands; Purinergic Receptors; Purinergic Signalling; P1 and P2 r |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-031-39725-7 |
| isbn_softcover | 978-3-031-39727-1 |
| isbn_ebook | 978-3-031-39725-7Series ISSN 1862-2461 Series E-ISSN 1862-247X |
| issn_series | 1862-2461 |
| copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl |
发表于 2025-3-21 17:39:50
