书目名称 | Protein Folding, Misfolding, and Disease | 副标题 | Methods and Protocol | 编辑 | Andrew F. Hill,Kevin J. Barnham,Roberto Cappai | 视频video | | 概述 | Brings together a thorough collection of cutting-edge methods for protein folding and misfolding.Features concise, step-by-step approaches to the varying topics.Includes key tips and implementation ad | 丛书名称 | Methods in Molecular Biology | 图书封面 |  | 描述 | .Protein misfolding is a key feature of many disorders in humans, given that over twenty proteins are known to misfold and cause disease. In .Protein Folding, Misfolding, and Disease: Methods and Protocols., experts in the field present a collection of current methods for studying the analysis of protein folding and misfolding, featuring strategies for expressing and refolding recombinant proteins which can then be utilized in subsequent experiments. This detailed volume also covers methods for analyzing the formation of amyloid, protocols for determining the size and structure of native and misfolded proteins, as well as specific examples of where misfolded proteins can be examined using state-of –the-art technologies. Written in the highly successful .Methods in Molecular Biology™. series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls..Up to date and authoritative, .Protein Folding, Misfolding, and Disease: Methods and Protocols. offers researchers the tools necessary to move ahead in this vital fi | 出版日期 | Book 2011 | 关键词 | Amyloid formation; Human disorders; Misfolded proteins; Native proteins; Protein structures; Recombinant | 版次 | 1 | doi | https://doi.org/10.1007/978-1-60327-223-0 | isbn_softcover | 978-1-4939-5689-0 | isbn_ebook | 978-1-60327-223-0Series ISSN 1064-3745 Series E-ISSN 1940-6029 | issn_series | 1064-3745 | copyright | Springer Science+Business Media, LLC 2011 |
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