书目名称 | Protein Folding and Misfolding |
副标题 | Shining Light by Inf |
编辑 | Heinz Fabian,Dieter Naumann |
视频video | |
概述 | Study of protein folding and misfolding Probe folding events over the time scale from picoseconds to minutes.Overview of the developments of infrared spectroscopy for protein studies.Strengths, advant |
丛书名称 | Biological and Medical Physics, Biomedical Engineering |
图书封面 |  |
描述 | Infrared spectroscopy is a new and innovative technology to study protein folding/misfolding events in the broad arsenal of techniques conventionally used in this field. The progress in understanding protein folding and misfolding is primarily due to the development of biophysical methods which permit to probe conformational changes with high kinetic and structural resolution. The most commonly used approaches rely on rapid mixing methods to initiate the folding event via a sudden change in solvent conditions. Traditionally, techniques such as fluorescence, circular dichroism or visible absorption are applied to probe the process. In contrast to these techniques, infrared spectroscopy came into play only very recently, and the progress made in this field up to date which now permits to probe folding events over the time scale from picoseconds to minutes has not yet been discussed in a book. The aim of this book is to provide an overview of the developments as seen by some of the main contributors to the field. The chapters are not intended to give exhaustive reviews of the literature but, instead to illustrate examples demonstrating the sort of information, which infrared technique |
出版日期 | Book 2012 |
关键词 | Infrared spectroscopy; Protein folding/misfolding; Protein studies; Time-resolved protein reactions; Tim |
版次 | 1 |
doi | https://doi.org/10.1007/978-3-642-22230-6 |
isbn_softcover | 978-3-642-27057-4 |
isbn_ebook | 978-3-642-22230-6Series ISSN 1618-7210 Series E-ISSN 2197-5647 |
issn_series | 1618-7210 |
copyright | Springer-Verlag Berlin Heidelberg 2012 |