书目名称 | Protein Amyloid Aggregation | 副标题 | Methods and Protocol | 编辑 | David Eliezer | 视频video | | 概述 | Includes cutting-edge methods and protocols for studying protein amyloid aggregation.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from t | 丛书名称 | Methods in Molecular Biology | 图书封面 |  | 描述 | .This detailed volume focuses on methods for the characterization of aggregation processes that lead to the formation of amyloid fibrils and amyloid oligomers which feature in the etiology of a variety of human disorders collectively known as amyloidoses. The scope of the collection includes techniques for visualizing early steps on the amyloid formation pathway, methods for capturing and characterizing oligomeric, potentially toxic, intermediates, strategies for preparing and characterizing mature amyloid fibrils and approaches for understanding templating and transmission of amyloid aggregates. Written in the highly successful .Methods in Molecular Biology. series format, the chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls..Authoritative and practical, .Protein Amyloid Aggregation: Methods and Protocols. serves as an ideal guide for biochemists and biophysicists with an interest in elucidating the mechanisms of protein amyloid formation, as well as chemists, pharmacologists and clinicians with an interest in leve | 出版日期 | Book 2016 | 关键词 | Aggregation processes; Amyloid fibrils; Amyloid formation pathway; Amyloidoses; Human disease; Pharmacolo | 版次 | 1 | doi | https://doi.org/10.1007/978-1-4939-2978-8 | isbn_softcover | 978-1-4939-5005-8 | isbn_ebook | 978-1-4939-2978-8Series ISSN 1064-3745 Series E-ISSN 1940-6029 | issn_series | 1064-3745 | copyright | Springer Science+Business Media New York 2016 |
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