| 书目名称 | Platinum-Based Drugs in Cancer Therapy |
| 编辑 | Lloyd R. Kelland,Nicholas P. Farrell |
| 视频video | |
| 概述 | Includes supplementary material: |
| 丛书名称 | Cancer Drug Discovery and Development |
| 图书封面 |  |
| 描述 | Leading international experts comprehensively review all aspects of platinum anticancer drugs and their current use in treatment, as well as examining their future therapeutic prospects. Writing from a variety of disciplines, these authorities discuss the chemistry of cisplatin in aqueous solution, the molecular interaction of platinum drugs with DNA, and such exciting new areas as DNA mismatch repair and replicative bypass, apoptosis, and the transport of platinum drugs into tumor cells. The emergent platinum drugs of the future-orally active agents, the sterically hindered ZD0473, and the polynuclear charged platinum BBR3464-are also fully considered. Timely and interdisciplinary, Platinum-Based Drugs in Cancer Therapy offers cancer therapeutics specialists an illuminating survey of every aspect of platinum drugs from mechanisms of action to toxicology, tumor resistance, and new analogs. |
| 出版日期 | Book 2000 |
| 关键词 | DNA; apoptosis; biochemistry; cancer; cancer therapy; chemistry; ovarian cancer; research; resistance; toxico |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-1-59259-012-4 |
| isbn_softcover | 978-1-61737-091-5 |
| isbn_ebook | 978-1-59259-012-4Series ISSN 2196-9906 Series E-ISSN 2196-9914 |
| issn_series | 2196-9906 |
| copyright | Springer Science+Business Media New York 2000 |
发表于 2025-3-21 19:58:07
