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Kurt Grünberg7]. These observations indicate that during the infection with HIV not only the peripheral immune system is disturbed but also the specialized local immune system termed gut associated lymphoid tissue (GALT). Therefore intestinal HIV/SIV-infection may represent a model for a mucosal immune defect.

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Impact of Design on the Sustainability of Mobile Applicationsmes more and more important to create a balance in the product-life-cycle. With regard to the design and sustainability of software the requirements to a programmer and the department of information technology in a company are getting higher, especially on mobile Applications (Apps) for mobile devic

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