| 书目名称 | Pharmacology and Applications of Naturally Occurring Iridoids | | 编辑 | Biswanath Dinda | | 视频video | | | 概述 | Examines the chemistry and distribution of iridoids in plants and insects.Analyses the biosynthesis of iridoids.Elucidates the pharmacology of iridoids and their application in medicine and agricultur | | 图书封面 |  | | 描述 | In this book, the author provides expert analysis on naturally occurring iridoids, their chemistry and their distribution in plants and insects. Particular attention is given to the pharmacology of iridoids and their prospective applications in pharmaceutical and agricultural industries. .Iridoids are found in a wide variety of plants and some insects, and they are structurally derived from monoterpenoid natural products. In the first two chapters of this book, the author describes the iridoids classification, occurrence and distribution in plants and insects. The following chapters cover different chromatographic and spectroscopic techniques that can be used to identify and quantify iridoids in herbal formulations, and also the biosynthesis of iridoids, in which the reader will discover a metabolomics and transcriptomics analysis to identify the genes involved in the biosynthesis. The final chapters provide insights on several pharmacological activities of iridoids, their physiological role in insects, pharmacokinetics in mammals, insects and microorganisms, and their applications in medicine and agriculture. ..This book will engage students and researchers interested in the chemi | | 出版日期 | Book 2019 | | 关键词 | Plant Iridoids; Chemistry of Iridoids; Pharmacology of Iridoids; Iridoids occurrence in Insects; Iridoid | | 版次 | 1 | | doi | https://doi.org/10.1007/978-3-030-05575-2 | | isbn_ebook | 978-3-030-05575-2 | | copyright | Springer Nature Switzerland AG 2019 |
| 1 |
,Classification of Iridoids, |
Biswanath Dinda |
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Abstract
Iridoids are the highly oxygenated monoterpenes, represented by the cyclopenta[c]pyranoid skeletal structure ., based on the structure of monoterpene iridane, 4,8-dimethyl-.-2-oxabicyclo-[4.3.0]-nonane ..
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| 2 |
,Occurrence and Distribution of Iridoids, |
Biswanath Dinda |
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Abstract
Iridoid monoterpenoids are widespread in the angiosperm plant families and are preferentially synthesized by the eudicots of Asterid clade. These are also synthesized by monocots. About sixty plant families have been reported to produce iridoids of diverse skeletal structures.
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| 3 |
,Isolation and Identification of Iridoids, |
Biswanath Dinda |
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Abstract
Diverse pharmacological activities of iridoids encouraged several chemists and pharmacologists for isolation of these compounds in large quantities in pure states for use as chemical standards as well as for further pharmacological studies. The separation and isolation of pure iridoid and secoiridoid glycosides and aglycones from crude plant extracts by conventional chromatographic systems such as thin-layer and column chromatographic methods are time consuming and require large amounts of organic solvents, and numerous chromatographic steps resulting in the lower recovery and higher cost for isolation.
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| 4 |
,Chemistry and Biosynthesis of Iridoids, |
Biswanath Dinda |
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Abstract
Potential health benefit effects and versatile pharmacological activities of several iridoids and secoiridoids have created interests among synthetic chemists and biotechnologists to make them popular targets of chemical synthesis and biosynthesis. The presence of oxidative substituents in the cyclopentane ring of iridoids, several groups have been used these compounds as starting materials for regioselective and stereoselective synthesis of potential bioactive alkaloids, prostaglandin analogues and other bioactive natural products.
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| 5 |
,Pharmacology of Iridoids, |
Biswanath Dinda |
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Abstract
In many Asian and European countries, medicinal plants have been used for a long time for the treatment of different ailments and diseases. In 400 ., Greek physician Hippocrates, known as the Father of Medicine, said ‘Food should be medicine and medicine should be food’ and elaborated on several dietary plants that could be prospective sources of medicine. Iridoids, an important class of secondary plant metabolites, have been found in several dietary folk medicinal plants of angiosperm plant families.
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| 6 |
,Pharmacokinetics of Iridoids, |
Biswanath Dinda |
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Abstract
Natural products are the most widely used low-cost drugs for commercial application in pharmaceutical industries. Several herbal products are utilized for treatment of various diseases due to their relative efficacy, safety, quality, cost and availability compared to related synthetic drugs. The low-cost and readily available herbal drugs are selected for commercial application after getting adequate evidence on efficacy, safety, and effective dosages from extensive clinical studies in animals and humans. The search for new drugs can be divided into two main phases: discovery and development from an industrial perspective. The former phase consists of evaluation of target enzymes or receptors for a particular disease and use of a variety of semiempirical structure–activity relationships after modification of the chemical structure of a natural drug to optimize the in vitro activity against a disease.
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| 7 |
,Applications of Iridoids in Pharmaceutical, Cosmetic, and Insecticide Industries, |
Biswanath Dinda |
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Abstract
A widely grown edible fruits and vegetables in different countries are rich in iridoid and phenolic contents. Bioactive iridoids present in these fruits and vegetables could be useful in commercial preparation of nutraceutical diet supplements and herbal drugs for prevention and treatment of various ailments and diseases.
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发表于 2025-3-21 16:08:58
