书目名称 | Peptide-Based Drug Design | 编辑 | Laszlo Otvos | 视频video | | 概述 | Presents full coverage of peptide-based drug development arranged in a sequential order as the leads proceed through the preclinical pipeline.Describes innovative and unusual technologies.Special focu | 丛书名称 | Methods in Molecular Biology | 图书封面 |  | 描述 | .Due to their high specificity and low toxicity profile, peptides have once again become central to the development of new drugs. In .Peptide-Based Drug Design: Methods and Protocols., expert researchers provide a handbook which offers a selection of research and production tools suitable for transforming a promising protein fragment or stand-alone native peptide into a pharmaceutically acceptable composition. The volume delves into contemporary, cutting-edge subjects such as hit isolation and target validation, computer-aided design, sequence modifications to satisfy pharmacologists, in vivo stability and imaging, and the actual production of difficult sequences. Written in the highly successful .Methods in Molecular Biology™. series format, chapters include readily reproducible, step-by-step laboratory protocols, lists of materials, and the Notes section, which highlights tips on troubleshooting and avoiding known pitfalls...Comprehensive and up-to-date, .Peptide-Based Drug Design: Methods and Protocols .shows its subject to be an independent science on the rise, and provides scientists with a clear, concise guide for continuing this vital research.. | 出版日期 | Book 2008 | 关键词 | Amino acid; Bioactive proteins; Drug development; Peptide chemistry; Peptide sequences | 版次 | 1 | doi | https://doi.org/10.1007/978-1-59745-419-3 | isbn_softcover | 978-1-61737-869-0 | isbn_ebook | 978-1-59745-419-3Series ISSN 1064-3745 Series E-ISSN 1940-6029 | issn_series | 1064-3745 | copyright | Humana Press 2008 |
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