书目名称 | Pattern Formation in Zebrafish | 编辑 | Lilianna Solnica-Krezel | 视频video | | 概述 | The first book that comprehensively describes the mechanisms of early patterning and morphogenesis in zebrafish.Summarizes the current knowledge and the key questions for the next decade of reseach.Al | 丛书名称 | Results and Problems in Cell Differentiation | 图书封面 |  | 描述 | What makes an ideal model system to study embryonic development? The answer to this question has varied in the course of scientific quest, depending on the available experimental approaches. Yet, at the beginning of the new millennium, most of the mainstream model organisms have one feature in common, they are amenable to genetic analysis. Indeed, the genetic approach has proven remarkably effective in the dissection of complex biological phenomena, starting with the regulation of the lactose operon in Escherichia coli, the decision between the lysogenic and lytic cycles of the lambda phage and the yeast cell cycle control. The genetic screens for mutations affecting embryonic development of a fruit fly, Drosophila melanogaster, carried out by Christiane Niisslein-Volhard, Eric Wieschaus and Edward Lewis, marked the turning point in experimental approaches to embryonic development of more complex organisms. The resulting mutants facilitated identification of the key regulatory molecules, while their phenotypic classes hinted at the underlying regulatory mechanisms. This work not only provided a paradigm for genetic dissection of other developmental processes, but also inspired many | 出版日期 | Book 2002 | 关键词 | Axis Formation; Danio; Danio rerio; Embryogenese; Embryonic Pattering; Endoderm; Gastrulation; Mesoderm; Neu | 版次 | 1 | doi | https://doi.org/10.1007/978-3-540-46041-1 | isbn_softcover | 978-3-642-07811-8 | isbn_ebook | 978-3-540-46041-1Series ISSN 0080-1844 Series E-ISSN 1861-0412 | issn_series | 0080-1844 | copyright | Springer-Verlag Berlin Heidelberg 2002 |
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