书目名称 | Patho-Epigenetics of Infectious Disease |
编辑 | Janos Minarovits,Hans Helmut Niller |
视频video | |
概述 | First book dedicated to Epigenetics of Infectious Disease.Deals with two major classes of infectious pathogens, i.e. bacteria and viruses.Comprehensive review of epigenetic reprogramming by bacteria a |
丛书名称 | Advances in Experimental Medicine and Biology |
图书封面 |  |
描述 | .Epigenetic modification of cellular genomes is a fascinating means of regulating tissue- and cell type-specific gene expression in all developmental stages of the life of an organism. Carefully orchestrated processes, such as DNA methylation and a plenitude of specific histone modifications secure the faithful transmission of gene expression patterns to progeny cells. Upon chronic infection, the epigenetic cellular balance can become disrupted and, in the long run, through the epigenetic reprogramming of host cell genomes, contribute to the malignant conversion of formerly healthy cells, in many cases preceded by the establishment of an epigenetic field of cancerization. The present volume undertakes to highlight the interactions of infectious pathogens and their effector molecules with the epigenetic regulatory machinery of the cell. Clearly, the recent take-off of epigenetics research did not leave Research on Infectious Diseases and Infection-Associated Cancer untouched. This resulted in a great many of clinically relevant data on understanding the molecular mechanisms of chronic infectious disease. Infectious pathogen- and disease-specific epigenetic alterations are already be |
出版日期 | Book 2016 |
关键词 | Epigenetics; Infectious Disease; DNA methylation; Histone modification; Epstein-Barr virus (EBV); Human I |
版次 | 1 |
doi | https://doi.org/10.1007/978-3-319-24738-0 |
isbn_softcover | 978-3-319-79669-7 |
isbn_ebook | 978-3-319-24738-0Series ISSN 0065-2598 Series E-ISSN 2214-8019 |
issn_series | 0065-2598 |
copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl |