| 书目名称 | Pancreatic Islet Isolation |
| 副标题 | From the Mouse to th |
| 编辑 | Miriam Ramírez-Domínguez |
| 视频video | |
| 概述 | Vivid and colourful illustrations.Presents state-of-the-art research and recent advances in islet isolation.A special chapter on the different and similar features between animal models and human isle |
| 丛书名称 | Advances in Experimental Medicine and Biology |
| 图书封面 |  |
| 描述 | Pancreatic islets make up the endocrine pancreas and they contain the only source of insulin in the body, beta cells. Hence, access to high quality preparations of pancreatic islets is fundamental for in vitro studies and to test pre-clinical applications in animal models in vivo. Access to healthy human islets is also crucial to improve transplantation procedures for diabetes. Given the susceptibility of pancreatic islets to the enzymatic digestion and mechanical stress required to obtain them, the isolation of islets is often considered as the delicate “work of a craftsman”. This book, which is aimed at beginners and experts alike, is a survey of the current state-of–the-art in this field and it centres on the challenges, pitfalls and peculiarities of pancreatic islet isolation in the different species used in pre-clinical and clinical applications. It explores the similarities and differences between human islets and those from other relevantspecies (rodents, pigs and non-human primates), and how these influence islet isolation. The ultimate goal of this book is to improve the outcome of islet isolation and transplantation in pre-clinical and clinical applications.. |
| 出版日期 | Book 2016 |
| 关键词 | Animal Models; Diabetes; Human Islet Isolation; Islet Purification; Translational Studies |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-319-39824-2 |
| isbn_softcover | 978-3-319-81974-7 |
| isbn_ebook | 978-3-319-39824-2Series ISSN 0065-2598 Series E-ISSN 2214-8019 |
| issn_series | 0065-2598 |
| copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl |
发表于 2025-3-21 17:25:09
